Factors Associated with Successful First-attempt Puncture in Pediatric Patients Undergoing Ultrasound-guided Peripherally Inserted Central Catheter

Background: Peripherally inserted central catheter (PICC) is an alternative to venous cannulation. This study aimed identify factors associated with first-attempt success rate in children undergoing PICC insertion. Methods: retrospective included pediatric patients who underwent placement at the Children’s Hospital of Zhejiang (1/2020-12/2020). The successful puncture was defined as smooth blood return and insertion guide wire. Clinical data were collected, identified by logistic regression analyses. Results: final analysis 640 (360 males, 56.2%). Successful first attempt achieved 380 (59.4%) patients. Multivariate revealed that being uncooperative after sedation (OR = 2.745, 95%CI: 1.028 - 7.331, P 0.044), cooperative 0.318, 0.128–0.791, 0.014), target vein depth (0.5 1 vs. ≤ 0.5: OR 1.715, 1.081–2.720, 0.022; 1.1-1.5 3.036, 1.166 7.903, 0.023; > 1.5 10.453, 2.366 46.139, 0.002), diameter (2.0 2.9 2: 0.313, 0.180 0.545, < 0.001; ≥ 3 0.122, 0.055 0.272, 0.001), 3F specification (vs. 1.9F: 2.057, 1.069 3.958, 0.031) independently failure attempt. Conclusions: degree cooperation, depth, rate.